On the primary day of the UK marketing campaign for COVID-19 vaccination, there have been reviews of two instances of anaphylaxis — a extreme, doubtlessly life-threatening allergic response — inside minutes of administration of the Pfizer/BioNTech mRNA vaccine. Subsequently additional instances of suspected anaphylaxis to the Pfizer vaccine had been reported. A brand new report revealed in Clinical & Experimental Allergy reveals that an allergy to the ingredient polyethylene glycol (PEG) is a trigger of anaphylaxis to the vaccine. However, that is within the context of tens of millions of doses safely administered.

The authors word that only a few persons are allergic to PEG, and so they present a information to figuring out those that are in danger. “This preliminary report confirms PEG as a cause of anaphylaxis to the Pfizer/BioNTech vaccine, for the first time,” they wrote. “COVID-19 vaccine anaphylaxis and PEG allergy are both rare, so proof of PEG as the cause in one case of vaccine anaphylaxis is important. However, it is important to emphasize that PEG allergy is rare and that COVID-19 vaccines remain safe.”

Reference: 7 April 2021, Clinical & Experimental Allergy.
DOI: 10.1111/cea.13874

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